Pulmonary vascular effects of pulsed inhaled nitric oxide in COPD patients with pulmonary hypertension

Abstract

Inhalation of pulsed NO with oxygen causes vasodilation in the pulmonary circulation of COPD patients, mainly in the well-ventilated areas. A high degree of heterogeneity was found in the level of vasodilation. Patients tend to feel better after the treatment. Chronic use trials are warranted.