PubMed · 1987 · 15 citations · 0 references
MedicineInfectious DiseasesVeterinary MicrobiologyAntimicrobial PharmacologyAntimicrobial PharmacotherapyOrthopedicsAntibiotic ProphylaxisBone InfectionsOsteomyelitisVeterinary Antimicrobial TherapyVeterinary BacteriologyBone Infection TherapyClindamycin TherapyOsteomyelitis Antibiotic ManagementStaphylococcal Infection TherapyStaphylococcus Aureus Soft Tissue InfectionVeterinary Antibiotic Therapy
Posttraumatic osteomyelitis attributable to Staphylococcus aureus infection was experimentally induced in 30 dogs, after which the dogs were treated with clindamycin at various dosage regimens. Of the regimens evaluated, oral administration of 11 mg of clindamycin/kg of body weight twice daily for 28 days was the most effective treatment for the osteomyelitis.