Binding of Folic Acid to Serum Proteins

Abstract

Binding of serum folic acid activity (FAA) to the protein fractions during and after pregnancy was studied by DEAE Sephadex A-50 gel chromatography. Towards the end of pregnancy, this binding increased. The increase was particularly distinct in the binding to transferrin. At the same time, the binding to α-2-macroglobulin decreased. Within a week after delivery, the total protein binding of FAA decreased remarkably. The decrease was also particularly distinct for transferrin