PubMed · 1999 · 15 citations · 0 references
MedicineNephrologyPathologyHepatologyRenal PathologyRenal PathophysiologyEosinophilic DisordersImmune-mediated Renal DiseaseInterstitial NephritisRenal DiseaseRenal ImmunopathologyUveal DiseaseEosinophilic InfiltratesEosinophilic Interstitial NephritisGranulomatous HepatitisGranulomatous Interstitial NephritisGranulomatous LesionsInterstitial Nephritis With UveitisLiver Enzyme AbnormalitiesPercutaneous Liver Biopsy
A 23-year-old male presented with renal failure, cholestatic liver enzyme elevation and uveitis. Percutaneous renal biopsy revealed marked eosinophilic infiltration of the renal interstitium, which made the diagnosis of TINU syndrome (Tubulo-Interstitial Nephritis and Uveitis). Percutaneous liver biopsy showed granulomatous hepatitis, which was not described as a part of TINU syndrome. The diagnostic dilemma and the literature are discussed.