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ERK/MAPK Signaling Drives Overexpression of the Rac-GEF, PREX1, in BRAF- and NRAS-Mutant Melanoma

DOIFull Paper Access

35

Citations

40

References

2016

Year

Meagan B. Ryan, Alexander J. Finn, Katherine H. Pedone, Nancy E. Thomas, Channing J. Der, Adrienne D. Cox
Molecular Cancer Research

Abstract

This study identifies an ERK-dependent mechanism that drives PREX1 upregulation and subsequent RAC1-dependent invasion in BRAF- and NRAS-mutant melanoma. Mol Cancer Res; 14(10); 1009-18. ©2016 AACR.

References

YearCitations

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