Publication | Open Access

Discovery and optimization of a series of imidazo[4,5-b]pyrazine derivatives as highly potent and exquisitely selective inhibitors of the mesenchymal–epithelial transition factor (c-Met) protein kinase

Molecular PharmacologyMedicinal ChemistryDrug TargetMedicineNatural SciencesRational Drug DesignMesenchymal–epithelial Transition FactorSelective InhibitorsProtein KinaseAnti-cancer AgentDrug DevelopmentPharmacologyCell BiologyPharmaceutical ChemistrySmall MoleculesDrug Discovery