Chinese herbal medicines promote hippocampal neuroproliferation, reduce stress hormone levels, inhibit apoptosis, and improve behavior in chronically stressed mice

Requirement of Hippocampal Neurogenesis for the Behavioral Effects of Antidepressants

Luca Santarelli, Michael Saxe, Cornelius T. Gross et al. · Science · 2003 · 4.3K citations · Full text

Neuropsychology, Psychotropic Medication, Chronic Antidepressants +18

Behavioural despair in rats: A new model sensitive to antidepressant treatments

Roger D. Porsolt, Guy Anton, N. Blavet et al. · European Journal of Pharmacology · 1978 · 3.1K citations

Experimental Psychopathology, Behavioral Sciences, Psychopathology +13

Stress-induced changes in cerebral metabolites, hippocampal volume, and cell proliferation are prevented by antidepressant treatment with tianeptine

Boldizsár Czéh, Thomas Michaelis, Takashi Watanabe et al. · Proceedings of the National Academy of Sciences · 2001 · 1.1K citations · Full text

Cell Proliferation in Adult Hippocampus is Decreased by Inescapable Stress: Reversal by Fluoxetine Treatment

Jessica E. Malberg, Ronald S. Duman · Neuropsychopharmacology · 2003 · 807 citations · Full text

Adult Hippocampus, Stress Hormone, Psychiatry +8

Opiates inhibit neurogenesis in the adult rat hippocampus

Amelia J. Eisch, Michel Barrot, Christina A. Schad et al. · Proceedings of the National Academy of Sciences · 2000 · 591 citations

Synaptic Plasticity, Substance Abuse, Psychoactive Drug +13