PubMed · 1999 · 35 citations · 0 references
MedicineInfectious DiseasesPediatricsBacteriologyNeonatologyPediatric Infectious DiseasesBacterial InfectionsCentral Nervous System InfectionsInfant Infectious DiseasesNeonatal InfectionsNeonatal Infectious DiseasesNeonatal SepsisBacterial Infections In NewbornsBacterial Meningitis TreatmentMeningitis Antibiotic TherapyNeonatal Bacterial InfectionNeonatal Cerebral InfectionNeonatal HydrocephalusNeonatal MeningitisPediatric Central Nervous System Infection
The subject of this report is the case of purulent meningitis in new-born caused by Klebsiella pneumoniae. As the intensive antibiotic therapy turned out to be ineffective phage therapy was applied. Oral administration of specific phage preparate for the period of 5 weeks resulted in complete sterilization of cerebrospinal fluid and unquestionable improvement of child's health. However, after several ventriculopunctures some complications appeared (haemorrhage into central nervous system, extra infection). They were treated in standard way. Because of increasing internal hydrocephalus and necessity of operation, the child was sent to suitable hospital for further treatment.