Expression of the colony stimulating factor-1 receptor (c-fms product) by cells at the human uteroplacental interface.

Abstract

These results suggest that CSF-1 may regulate invasion and differentiation of human placental trophoblast, depending upon the spatial and temporal distribution of its receptor. CSF-1 may also influence placental development and function by acting via decidual and fetal macrophages, which are the other cell populations expressing the receptor.