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Antibody and cell-mediated immunity to herpes simplex virus in psychotic depression.
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1978
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Psychotic DepressionImmunologySimplex VirusMental HealthPsychologySocial SciencesMood SymptomCell-mediated ImmunityNeuroimmunologyPsychoneuroimmunologyPsychiatryDepressionAcute Hsv InfectionPsychiatric DisorderMood SpectrumSchizophreniaBiological PsychiatryHsv InfectionMedicinePsychopathologyPost-traumatic Stress Disorder
The incidence and antibody titers to herpes simplex virus (HSV) were found significantly higher in patients with psychotic depression as compared to normal controls. Furthermore, the cell-mediated immunity (CMI) to HSV in psychotic depression was similar to that observed after acute HSV infection or recurrence. The results suggest therefore an association between HSV infection and psychotic depression.