MedicinePharmacologyPharmacotherapyClinical PharmacologyEndocrine PharmacotherapyReproductive EndocrinologyHormonal ManagementHormonal TherapyPolycystic Ovary SyndromeReproductive Endocrine PharmacotherapyReproductive Endocrinology PharmacotherapyReproductive PharmacologyBromocriptine TreatmentHormonal Contraceptive TherapyOvulatory FunctionPolycystic Ovary Syndrome ManagementPolycystic Ovary Syndrome PharmacotherapyPolycystic Ovary Syndrome TreatmentPolycystic Ovary Syndrome-related Menstrual DysfunctionSpironolactone Therapy
Marked improvement in the severe hypertension (250/150 mmHg) and hirsutism of a patient suffering from polycystic ovary syndrome was quickly achieved by the use of spironolactone 200 mg per day. Substitution of spironolactone with bromocriptine induced further amelioration of these symptoms and renewal of ovulatory cycles. These drugs may afford another mode of therapy in patients with polycystic ovary syndrome.