MedicinePathologyCellular PathologyHistopathologyImmunopathologyGranulomatous InflammationInflammatory Disease PathologyInflammatory LesionsPulmonary InflammationPulmonary PathologyCellular Inflammatory ResponsesGranuloma NecrosisGranulomatous LesionsGranulomatous Lung InflammationInfiltrationInflammatory Cellular ChangesSarcoid GranulomasTissue Infiltration By Inflammatory Cells
16 patients of Wegener's granulomatosis, 4 of allergic angiitis and granulomatosis, 3 of lymphomatoid granulomatosis and 1 of necrotizing sarcoid granulomatosis were reported. In this group of different diseases, characteristic pathological manifestations are inflammatory cellular infiltration of vessel wall combined with destruction and necrosis of pulmonary parenchyma. There was little difference in their clinical features. In most of the cases, fever and systemic symptoms related to lung and extrapulmonary organs were present. Correct diagnosis of these diseases is very important, because both the prognosis and therapy are different. As for the prognosis, it ranges from benign (necrotizing sarcoidal granulomatosis) to very malignant (lymphomatoid granulomatosis). The clinical features of each illness were reviewed with emphasis on their histopathologic findings. The therapeutic effect and final outcome were followed.