Relationship between genetic polymorphisms of drug efflux transporter MDR1 (ABCB1) and response to losartan in hypertension patients. - Concepedia

Concepedia

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Relationship between genetic polymorphisms of drug efflux transporter MDR1 (ABCB1) and response to losartan in hypertension patients.

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References

2016

Year

Göktaş Mt, Funda Pepedil, Orhan Furkan Karaca, Said Kalkışım, Lokman Çevik, Ersin Gümüş, Guven Gs, Babaoglu Mo, Atilla Bozkurt, Ümit Yaşar

Abstract

This study revealed that hypotensive response to losartan was significantly affected by the C3435T genetic polymorphism of MDR1 and hypertensive patients with MDR1 3435T allele may present a better response to losartan treatment.