¹¹C-Methionine PET of Myocardial Inflammation in a Rat Model of Experimental Autoimmune Myocarditis

Abstract

In a rat model of autoimmune myocarditis, we demonstrated the colocalization of radiolabeled methionine accumulation with ¹⁸F-FDG uptake in histologically proven inflammatory lesions. These data suggest that ¹¹C-methionine might represent a promising candidate for the noninvasive detection and monitoring of myocarditis.