AgSCF₃-Mediated Oxidative Trifluoromethythiolation of Alkynes with Dearomatization to Synthesize SCF₃-Substituted Spiro[4,5]trienones

Abstract

A new method for the AgSCF3-mediated radical cascade difunctionalizing trifluoromethythiolation of alkynes with dearomatization is developed. This protocol provides a novel route to SCF3-substituted spirocyclic compounds via the formation of one C-SCF3 bond, one C-C bond, and one C-O double bond in a single step.