Stimulation of DNA synthesis in human fibroblasts by human pancreatic secretory trypsin inhibitor.

Abstract

Human pancreatic secretory trypsin inhibitor stimulated [3H]thymidine incorporation into DNA in human fibroblasts at concentrations present in human serum. Combined addition of human pancreatic secretory trypsin inhibitor and porcine insulin gave more than additive stimulation of [3H]thymidine incorporation.