Eurosurveillance · 2009 · 198 citations · 0 references
Life SciencesInfectious DiseasesMicrobiologyMedical MicrobiologyMolecular VirologyVirologyArboviral DiseasesEmerging Viral DiseasesMosquito BiologyMosquito-borne DiseasesViral InfectionsViral PathologyDeceased Donor Liver TransplantationHuman Neuroinvasive DiseaseMosquito-borne Disease InvestigationMosquito-borne Disease RiskNeurological Viral InfectionsUsutu Virus DiseaseUsutu Virus InfectionViral Neurologic Disease
We report a case of Usutu virus (USUV)-related illness in a patient that underwent an orthotropic liver transplant (OLT). Post transplant, the patient developed clinical signs of a possible neuroinvasive disease with a significant loss of cerebral functions. USUV was isolated in Vero E6 cells from a plasma sample obtained immediately before the surgery, and USUV RNA was demonstrated by RT-PCR and sequencing. This report enlarges the panel of emerging mosquito-borne flavivirus-related disease in humans.