PubMed · 1989 · 15 citations · 0 references
Life SciencesPhysiologyVeterinary PhysiologyCardiothoracic SurgeryClinical CardiologyExercise PhysiologyCardiac PhysiologyCardiovascular PhysiologyMechanical Circulatory SupportMuscle MechanicsMuscle PhysiologyCardiac Muscle ContractionCardiac OutputPower OutputRight Ventricular Assist DevicesRight Ventricular ContractilityRight Ventricular MechanicsRight Ventricular PhysiologyRight Ventricular Preload
Skeletal muscle ventricles (SMV) were constructed from canine latissimus dorsi muscle and chronically stimulated to pump fluid within a totally implantable mock circulation device. They were stimulated to contract at either 95/min (N = 7) or 54/min (N = 4). The preload was chronically maintained at 20 mmHg. After 1 month of continuous pumping the SMV were capable of generating a stroke work of 0.134 X 10(6) ergs and power output of 0.021 watts, representing 61% and 42% of the stroke work and power output of the native canine right ventricle, respectively.