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Cytochromes P‐450 and bs in human liver microsomes
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1969
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Molecular PharmacologyToxicologyHepatotoxicityHuman MetabolismHealth SciencesBiochemistryLiver PhysiologyCytochromes P‐450MetabolomicsPharmacologyDrug-induced Liver InjuryHuman LiverHepatologyLiver DiseaseMetabolismMedicinePharmacokineticsCarbon MonoxideDrug Analysis
Cytochromes P‐450 and b, have been demonstrated in human liver microsomes. The carbon monoxide and ethyl isocyanide difference spectra of cytochrome P‐450 in human liver are similar to those observed with rat or rabbit liver. The kinetic properties of 3,4‐benzpyrene hydroxylase in human liver have been determined.