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Cerebral infarct precipitated by praziquantel in neurocysticercosis--a cautionary note.
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1988
Year
ThrombosisParasitic DiseaseAntiparasitic AgentStrokeNeurological DisorderMalariaCerebral InfarctPraziquantel TherapyMassive Inflammatory ResponseBrain InjuryNeurologyCerebral Blood FlowNeuropathologyMedicineNeuroimmunologyHeavy Parasite LoadsParasitology
A patient who developed a cerebral infarct during the course of praziquantel therapy for neurocysticercosis is described. Destruction of a large number of cysts by praziquantel followed by a massive inflammatory response was likely to have precipitated the event. Caution on the use of this drug in patients with heavy parasite loads is emphasized.