Concepedia

Publication | Open Access

Neoadjuvant Chemotherapy Modulates the Immune Microenvironment in Metastases of Tubo-Ovarian High-Grade Serous Carcinoma

DOIFull Paper Access

153

Citations

34

References

2016

Year

Steffen Böhm, Anne Montfort, Oliver M.T. Pearce, Joanne Topping, Probir Chakravarty, Gemma Everitt, Andrew Clear, Jackie R. McDermott, Darren Ennis, Thomas Dowe,
Clinical Cancer Research

Abstract

NACT may enhance host immune response but this effect is tempered by high/increased levels of PD-1, CTLA4, and PD-L1. Sequential chemoimmunotherapy may improve disease control in advanced HGSC. Clin Cancer Res; 22(12); 3025-36. ©2016 AACR.

References

YearCitations

Page 1