Partition Model–Based ^99mTc-MAA SPECT/CT Predictive Dosimetry Compared with ⁹⁰Y TOF PET/CT Posttreatment Dosimetry in Radioembolization of Hepatocellular Carcinoma: A Quantitative Agreement Comparison

Abstract

In ⁹⁰Y radioembolization of HCC, predictive dosimetry based on ^99mTc-MAA SPECT/CT provided good estimates of absorbed doses calculated from posttreatment ⁹⁰Y TOF PET/CT for tumor and nontumor tissues. The low variability of [Formula: see text] demonstrates that pretreatment dosimetry is particularly suitable for minimizing radiation-induced hepatotoxicity.