PubMed · 1990 · 10 citations · 0 references
MedicineOrthopaedic SurgerySurgeryMusculoskeletal InfectionOrthopedicsWound HealingBone InfectionsOrthopedic InfectionPostoperative Wound CareWound DebridementFracture HealingMuscle FlapsPostoperative Wound ManagementSoft Tissue Coverage ManagementSoft Tissue Defect CoverageTibial Shaft FracturesTreatment Protocol Evaluation
93 patients with grade III open tibial fractures were treated without a treatment protocol from 1980 to 1982. This group is compared to 147 pts. managed between 1983 to 1986 according to a standardized prospectively designed protocol with aggressive debridement augmented by pulsatile Jet-lavage. Serial debridement were performed at 48-hour intervales until early soft-tissue coverage were obtained using local or free muscle-flaps. The mean follow-up was 80 months respectively 44 months. --The aggressive regimen led to a statistically significant decrease in infection (30% vs 12%), nonunion (16% vs 6%), amputation (18% vs 6%) and combined hospitalization-periods (137 vs 74 days) [all p less than 0.001]. The aggressively treated groups showed a trend toward early fracture-healing (30 vs 23 weeks) although this was not statistically significant.