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Scaffold-hopping of bioactive flavonoids: Discovery of aryl-pyridopyrimidinones as potent anticancer agents that inhibit catalytic role of topoisomerase IIα

Medicinal ChemistryBiochemistryTopoisomerase IiαBioactive FlavonoidsPotent Anticancer AgentsMedicineNatural SciencesAnti-cancer AgentDrug DevelopmentPharmacologyPharmaceutical ChemistryInhibitory ActivityDrug Discovery