Serum and synovial fluid concentrations of cold‐inducible <scp>RNA</scp>‐binding protein in patients with rheumatoid arthritis

Abstract

The serum and synovial concentrations of CIRP in the RA patients were increased compared to the OA patients. Additionally, the synovial concentration of CIRP in RA patients correlated well with disease activity, that is, the DAS28-ESR/CRP. Based on these results, CIRP mediates inflammation and is a potential marker for synovial inflammation.