PubMed · 1985 · 10 citations · 0 references
MedicineObstetricsPharmacologyObstetric AnesthesiaObstetric AnesthesiologyPain ManagementAdverse Effects Of AnalgesicsAnalgesiaAnalgesic PharmacologyPain Management In LaborAnalgesia In ParturitionAnalgesia Side EffectsIntravenous Self-administrationLabor Analgesia SafetyPeripartum AnalgesiaPeriparturient AnalgesiaPharmacologic AnalgesiaSelf-administration Comparison
Pentazocine or pethidine was administered to healthy parturients up to the time of delivery using a self-demand (self-administration on demand) intravenous apparatus, the Cardiff Palliator. Good analgesia was obtained with both drugs. The patients receiving pethidine exhibited side-effects (nausea, vomiting and drowsiness), whereas there were no side-effects among those receiving pentazocine. Apgar and neurobehavioural scores of the babies of mothers in both groups were the same and did not differ from those of a third group of babies, the mothers of whom had received 4-hourly intramuscular pethidine on demand according to the usual hospital routine. The self-administration technique proved a safe and effective means of providing analgesia during labour and delivery, with pentazocine having a decided advantage over pethidine because of its lack of side-effects.