A new algorithm for the discrimination of actinic keratosis from normal skin and squamous cell carcinoma based on <i>in vivo</i> analysis of optical properties by high‐definition optical coherence tomography

Abstract

HD-OCT seems to enable the combination of in vivo morphological analysis of cellular and 3D microarchitectural structures with in vivo analysis of optical properties of tissue scatterers in AK/SCC lesions and normal sun-exposed skin. In vivoHD-OCT analysis of optical properties permits AK discrimination from SCC and AK subdifferentiation with higher accuracy than in vivoHD-OCT analysis of morphology alone.