The prevention of oral complications in bone-marrow transplantations by means of oral hygiene and dental intervention.

Abstract

Oral complications cause morbidity and mortality in patients, undergoing allogeneic or autologous bone-marrow transplantation. The clinical features and the pathogenesis of the oral sequelae of bone marrow ablative therapy and graft-versus-host disease are discussed. In addition, a preventive oral care procedure before, during and after bone-marrow transplantation is proposed.