PubMed · 1977 · 21 citations · 0 references
Veterinary MedicineImmunologyPathologyHypersensitivityImmunopathologyInflammationHypersensitivity PneumonitisHypersensitivity ReactionsImmune-mediated DiseaseImmune-mediated InjuryImmunological Disease ModelsAcute Hypersensitivity PneumonitisAcute Immune InjuryAnimal Challenge ModelsAnimal Disease ModelsChronic Immune InjuryHypersensitivity Tissue InjuryImmune Complex InjuryImmune-mediated Pneumonitis
The etiology of hypersensitivity pneumonitis has been ascribed to each major type of immune injury. Data obtained from animal models support the spontaneous human situation in which a contunuum of events results in disease. The major attempts at gaining insight into this disease spectrum through animal models are reviewed.