PubMed · 1987 · 21 citations · 0 references
MedicineOncologyPharmacologyCancer PharmacologyChemotherapyMedical OncologyChemotherapy In Hematologic MalignanciesCombination ChemotherapyCytotoxic ChemotherapyChemotherapy Administration In LymphomaCytarabine-based RegimensLymphoma ChemotherapyLymphoma Treatment ResponseNon-hodgkin Lymphoma TherapyNon-hodgkin Lymphoma TreatmentPhase Ii InvestigationRefractory Non-hodgkin Lymphoma
A phase II trial of cytarabine, cisplatin, and etoposide was conducted in 38 patients with refractory stage III and IV non-Hodgkin's lymphoma. There were two complete and nine partial responses (32%) among 35 evaluable patients. Response rate in patients with large cell lymphoma was 45%. The dose-limiting toxic effect was myelosuppression in 66% of patients.