PubMed · 1976 · 21 citations · 0 references
Life SciencesGeneticsObstetricsCytogeneticsHuman GeneticsReproductive GeneticsChromosomal AbnormalitiesChromosome AberrationsChromosome BandingMolecular CytogeneticsNumerical Chromosome AbnormalitiesStructural Chromosome AbnormalitiesChromosome Banding PatternsConstitutional Chromosome AbnormalitiesCytogenetic AbnormalitiesFetal Chromosomal AbnormalitiesReproductive Cytogenetics
Banding technique were applied to cell lines which had been established earlier from spontaneous human abortions and preserved frozen. Most of the autosomes were shown to be involved in lethal trisomies. As a result of the precise identification of affected chromosomes, the exact time of developmental arrest as well as certain phenotypes could be correlated with the various trisomies.