Synthesis of N<sup>1</sup>-4-Pyridazinylsulfanilamide Derivatives. II

Abstract

N1-[6-Methoxy (or Ethoxy Butoxy)-4-pyridazinyl] sulfanilamide (XIV) was synthesized from 4-amino-6-pyridazinol (I), 4-amino-3, 6-dichloropyridazine (VI), or 4-amino-5, 6-dichloropyridazine (XVIII). Reaction of 4 (or 5)-ethoxy-6-chloropyridazine (XVIII) with ammonia only gave 4 (or 5)-amino-6-chloropyridazine (XIX).