Transport of some mono- and di-saccharides into yeast cells

Abstract

Finally the present results indicate that polyphloretin phosphate, polyphlorrhizin phosphate and polyhesperidin phosphate as well as polyoestradiol phosphate inhibit seminal acid phosphatase. These polymeric phosphates inhibit other enzymes as well (Diczfalusy et at. 1953, Ferno et al. 1953, 1958). It is thus very likely that the inhibi- tion of acid phosphatase by these compounds is just an example of a widespread and non-specific action of high molecular-weight polyelectrolytes on several enzymes, as suggested by Spensley & Rogers (1954). The reversibility of the enzyme in- hibition also suggests a macro-anion-macro-cation interrelationship similar to that postulated by these authors for the interaction between polyphloretin phosphate and protamine on hyaluronidase or between heparin and polylysine on pepsin. SUMMARY 1. The hydrolysis of monophenyl phosphate by unpurified human seminal acid phosphatase has been investigated.