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Clinical features of inflammatory joint and spine manifestations in Crohn's disease.
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1986
Year
Joint InflammationInflammatory JointGastroenterologyPathologyClinical FeaturesSpine ManifestationsOrthopaedic SurgeryInflammatory ArthritisAxial SpondyloarthritisInflammationRheumatoid DisorderChildhood ArthritisInflammatory Rheumatic DiseaseSpine InflammationUlcerative ColitisRheumatoid ArthritisRheumatologyAutoimmune DiseaseSpondyloarthritisRheumatic DiseasesPaediatric RheumatologyInflammatory DiseaseMedicineBowel Disease
167 patients with Crohn's disease were investigated for joint and spine inflammation. Arthritis was observed in 23 patients (14%), sacroiliitis in 24 (14%), and sacroiliitis in combination with arthritis in 11 patients (7%). 15 patients (9%) had ankylosing spondylitis; 9 of them were HLA-B27 positive (60%). A parallel pattern in the course of bowel disease and joint inflammation was observed in 22 out of 34 patients with arthritis (59%). An association between the localization of Crohn's disease and the type of spondylarthritis could not be demonstrated. Patients with arthritis alone developed erythema nodosum (35%) or aphthous stomatitis more often (21%) than patients without spondylarthritis+ (6% and 12%, respectively). Other extra-intestinal manifestations of Crohn's disease did not reveal any association with the development of spondyloarthritis.