Comparison of two serotype 1 MDV isolates.

Miles Am, Anderson As, Bernberg El, Joan L. Kent, Rosenberger Jk, Pope Cr, Morgan Rw

PubMed · 2000 · 10 citations · 0 references

Concepts

Abstract

We compared the RB1B and T. King (TK) serotype 1 isolates of Marek's disease virus (MDV) in vivo. Body and organ weights, mortality, and lesions indicated that the TK inoculum established early infection more efficiently than RB1B and did greater damage to the bursa of Fabricius and thymus. Subsequent studies showed that the TK inoculum that we used contained chicken infectious anemia virus (CIAV). Therefore, pathogenicity profiles shown here should be interpreted with the presence of CIAV contamination in the TK stock in mind.