PubMed · 2011 · 19 citations · 5 references
Public HealthChild HealthPediatricsInfant HealthPediatric EpidemiologyPediatric PulmonologyGastroesophageal Reflux DiseaseRespiratory DiseaseRespiratory Disease Epidemiology In ChildrenChildhood Wheezing EpidemiologyEnvironmental FactorsGastroesophageal Reflux ComorbidityMale-to-female RatioPediatric Gastroesophageal Reflux Disease
Sixty-seven children less than two years of age with recurrent wheezing were evaluated clinically and demographically by proper history and clinical examinations. The mean age of the study subjects at enrolment and at onset of wheezing was 10.8 + 5.24 months and 7.1 + 3.857 months, respectively. The male-female ratio was 9:2. The majority of these cases (82%) had onset of wheezing at less than 1 year of age. One-third of the cases were diagnosed as asthma and viral infection associated wheeze. Increasing age in the first 2 years of life was significantly associated with decreasing trend of cases with history suggestive of reflux. The children with wheeze due to causes other than gastroesophageal reflux were more likely to be not exclusively breast fed. The present study did not find any significant difference in the prevalence of various socioeconomic, environmental factors and clinical factors among the various types of the early wheezers.
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Asthma and Wheezing in the First Six Years of Life
Fernando D. Martínez, Anne L. Wright, Lynn M. Taussig et al. · New England Journal of Medicine · 1995 · 3.8K citations · Full text
Medicine, Child Health, Pediatrics +13
Characterization of wheezing phenotypes in the first 10 years of life
Ramesh Kurukulaaratchy, M. Fenn, Linda Waterhouse et al. · Clinical & Experimental Allergy · 2003 · 186 citations · Full text
Medicine, Child Health, Pediatrics +17