Pharmacological activity of<i>Costus spicatus</i>in experimental<i>Bothrops atrox</i>envenomation

Abstract

The data suggest that CSE could exhibit a central mechanism for pain inhibition, and may also inhibit prostaglandin synthesis. These findings corroborate the traditional administration of C. spicatus decoction to treat inflammatory disorders, including those caused by B. atrox envenomation.