Electrochemotherapy of skin tumours: comparison of two electroporation protocols.

Abstract

The efficiency of electrochemotherapy in cutaneous non-melanoma tumours depends on the duration of electric pulses. For biphasic pulses, duration below 50 mus per phase (or 50+50 mus for the total pulse) is not recommended, in spite of a markedly reduced pain sensation. The rule about equal efficiency of larger number of shorter pulses and longer pulses of lesser number has its limits for external application, especially through the skin.