ELF3 modulates type II collagen gene (<i>COL2A1</i>) transcription in chondrocytes by inhibiting SOX9-CBP/p300-driven histone acetyltransferase activity - Concepedia

Concepedia

Publication | Open Access

ELF3 modulates type II collagen gene (<i>COL2A1</i>) transcription in chondrocytes by inhibiting SOX9-CBP/p300-driven histone acetyltransferase activity

DOI Full Paper Access

47

Citations

64

References

2016

Year

Miguel Otero, Haibing Peng, Karim El Hachem, Kirsty L. Culley, Elisabeth Wondimu, J. Quinn, Hiroshi Asahara, Kaneyuki Tsuchimochi, Ko Hashimoto, Mary B. Goldring

Connective Tissue Research

Abstract

Our results highlight the contribution of ELF3 to transcriptional regulation of COL2A1 and its potential role in OA disease, and uncover epigenetic mechanisms at play in the regulation of ELF3 and its downstream targets in articular chondrocytes.

References

	Year	Citations

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