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Publication | Open Access

Nuclear-targeting TAT-PEG-Asp8-doxorubicin polymeric nanoassembly to overcome drug-resistant colon cancer

DOIFull Paper Access

26

Citations

16

References

2016

Year

Zhenzhen Pan, Huiyuan Wang, Meng Zhang, Tingting Lin, Wenyuan Zhang, Pengfei Zhao, Yisi Tang, Yong Xiong, Zeng Yuan-er, Yongzhuo Huang
Acta Pharmacologica Sinica

Abstract

TAT-PEG-Asp8-Dox NPs can increase cellular drug uptake and intranuclear drug delivery and retain effective drug accumulation inside the cells, thus exhibiting enhanced anticancer activity toward the drug-resistant human colon cancer HCT8/ADR cells.

References

YearCitations

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