Poliomyelitis Virus in Blood of Orally Infected Monkeys and Chimpanzees.

Abstract

SummarySeven of 10 cynomolgus monkeys and 3 of 4 chimpanzees have been found to have viremia early in the incubation period following oral infection with poliomyelitis virus. Viremia was present in animals infected with a Brunhilde type (Egypt) as well as a Lansing type (Y-SK), and persisted in some animals over the 4th, 5th, and 6th days after virus ingestion. Virus was not isolated from blood specimens collected during the first 3 days after feeding, nor on the 7th day, in the two instances in which it was tested. The interval between viremia and the appearance of paralysis varied between 3 and 7 days in the cynomolgus monkeys.