PubMed · 1989 · 19 citations · 0 references
MedicineOncologyOtolaryngologyHead OncologyNeck OncologyNeuro-oncologyBone TumorsCentral Nervous System TumorsCranial Nerve TumorsSkull Base ImagingSkull Base SurgerySkull Base TumorsChondrosarcoma GradingChondrosarcoma SurgeryChordoma ImagingPatient History AssessmentRadiologic ImagingSkull Base MalignanciesSkull Base ResectionSkull Base Tumor Imaging
Chondrosarcoma of the skull base is a rare neoplasm. The most common presenting symptoms are hoarseness, dysphagia, and diplopia, which is associated with palsies of cranial nerves X, IX, and VI. The temporal bone is the most common site of tumor origin, followed by the sphenoid bone. These tumors must be differentiated from chordoma, chondroid chordoma, osteogenic sarcoma, enchondroma, and meningioma. Diagnosis is made by patient history, radiologic imaging, and biopsy. The treatment is surgical excision followed by radiation therapy. Five-year survival rates for grades I, II, and III are 90, 81, and 43%, respectively.