Concepedia

Publication | Open Access

The Cytosolic NADPH Oxidase Subunit NoxO1 Promotes an Endothelial Stalk Cell Phenotype

DOIFull Paper Access

26

Citations

27

References

2016

Year

Ralf P. Brandes, Sabine Harenkamp, Christoph Schürmann, Ivana Josipovic, Beliza Rashid, Flávia Rezende, Oliver Löwe, Franziska Moll, Jeremy Epah, Jeanette Eresch,
Arteriosclerosis Thrombosis and Vascular Biology

Abstract

NoxO1 stimulates α-secretase activity probably through reactive oxygen species-mediated oxidation. Deletion of NoxO1 attenuates Notch signaling and thereby promotes a tip-cell phenotype that results in increased angiogenesis.

References

YearCitations

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