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Vasopressin response and terbutaline inhibition of the uterus.
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1976
Year
FertilityGynecologyMenstrual CycleReproductive EndocrinologyReproductive MedicineObstetricsPublic HealthMedicineMaternal HealthVascular BiologyVasopressin ResponseEndocrinologyPharmacology8-Lysine VasopressinUterine Vascular BedOvarian HormonePhysiologyBeta2 Receptor StimulationReproductive Hormone
A study of the effects of 8-lysine vasopressin (LVP) and its long-acting analogue N-a-triglycyl-8-lysine vasopressin (TGVP) on the myometrium and vasculature of the normal human nonpregnant uterus was undertaken. The results suggest that the vasopressins decrease local endometrial blood flow both directly by effects on the uterine vascular bed, and indirectly by increasing myometrial activity. The effects in vivo can be effectively counteracted by beta2 receptor stimulation.