Concepedia

Publication | Closed Access

Genetic changes in uroepithelial tumors of patients with Balkan endemic nephropathy.

11

Citations

0

References

2003

Year

Srebrena Y Atanassova, Tzvetan D Gergov, E. Todorovska, Ivana G Roeva, Tchavdar H Georgiev, Joanna Fink-Gremmels, Boriana Zaharieva
PubMed

Abstract

The LOH suggests the presence of a new, so far unidentified tumor-suppressor gene at 3q24. In pTa BEN tumor CGH showed genome instability was extremely high. The 24-color FISH indicated highly complex chromosomal rearrangements. Chromosome 3 anomalies support our previous data on 3q24 - 3q26.3 association with BEN.