BAT1 promoter polymorphism is associated with rheumatoid arthritis susceptibility. - Concepedia

Concepedia

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BAT1 promoter polymorphism is associated with rheumatoid arthritis susceptibility.

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References

2008

Year

Adolfo Quiñones‐Lombraña, Alejandro López‐Soto, Francisco Javier Ballina‐García, Mercedes Alperí, Rubén Queiró, Antonio López‐Vázquez, Carlos López‐Larrea, Segundo González

Abstract

The BAT1 -348T polymorphism is associated with RA susceptibility independently of HLA-DRB1. The role of BAT1 in the regulation of tumor necrosis factor-a suggests that BAT1 may regulate the inflammatory response observed in patients with RA.