Intravesical Chemotherapy in a Controlled Trial with Thio-Tepa Versus Doxorubicin Hydrochloride

Abstract

No AccessJournal of Urology1 May 1981Intravesical Chemotherapy in a Controlled Trial with Thio-Tepa Versus Doxorubicin Hydrochloride Yoav Horn, Abraham Eidelman, Natalio Walach, and Mahmoud Ilian Yoav HornYoav Horn More articles by this author , Abraham EidelmanAbraham Eidelman More articles by this author , Natalio WalachNatalio Walach More articles by this author , and Mahmoud IlianMahmoud Ilian More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)55151-4AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail We treated 25 patients with recurrent transitional cell carcinoma of the bladder with intravesical chemotherapy. The 2 drugs used were doxorubicin hydrochloride and thio-tepa introduced at 3-week intervals and checked for efficacy by repeated cystoscopy after every 3 instillations. The clinical data and results of both groups are presented, and the importance of intravesical treatment with minimal toxicity in this relatively benign condition is discussed. © 1981 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited BySeraphim L, Perrapato S, Slocum H, Rustum Y and Huben R (2018) In Vitro Study of the Interaction of Doxorubicin, Thiotepa, and Mitomycin-C, Agents Used for Intravesical Chemotherapy of Superficial Bladder CancerJournal of Urology, VOL. 145, NO. 3, (613-617), Online publication date: 1-Mar-1991.Okamura T, Ohtani M, Inoue K, Fukushima S, Ohtaguro K and Kakizoe T (2018) Effects of Intravesical Instillation of Antitumor Chemotherapeutic and Immunotherapeutic Agents on Bladder Lesion Development in Rats Pretreated with N-Butyl-N-(4-Hydroxybutyl)NitrosamineJournal of Urology, VOL. 138, NO. 5, (1305-1307), Online publication date: 1-Nov-1987.Crawford E, McKenzie D, Mansson W, Totonchy M, Grossman H, Davis M, Lamm D and Duchek M (2018) Adverse Reactions to the Intravesical Administration of Doxorubicin Hydrochloride: Report of 6 CasesJournal of Urology, VOL. 136, NO. 3, (668-669), Online publication date: 1-Sep-1986.Leissner K and Gustavsson B (2018) Intravesical High Dose 5-Fluorouracil Instillations Combined with Allopurinol—A Therapeutic Alternative in the Treatment of Multiple Bladder TumorsJournal of Urology, VOL. 132, NO. 1, (34-36), Online publication date: 1-Jul-1984.Engelmann U, Bürger R, Rumpelt J and Jacobi G (2018) Adriamycin Permeability of the Rat Bladder under Different ConditionsJournal of Urology, VOL. 129, NO. 4, (862-864), Online publication date: 1-Apr-1983. Volume 125Issue 5May 1981Page: 652-654 Advertisement Copyright & Permissions© 1981 by The American Urological Association Education and Research, Inc.MetricsAuthor Information Yoav Horn More articles by this author Abraham Eidelman More articles by this author Natalio Walach More articles by this author Mahmoud Ilian More articles by this author Expand All Advertisement PDF DownloadLoading ...