Serum level of transforming growth factor-beta1 (TGF-beta1) and the expression of TGF-beta receptor type II in peripheral blood mononuclear cells in patients with autoimmune hepatitis. - Concepedia

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Serum level of transforming growth factor-beta1 (TGF-beta1) and the expression of TGF-beta receptor type II in peripheral blood mononuclear cells in patients with autoimmune hepatitis.

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2005

Year

Kohsaku Sakaguchi, Motoko Kitano, Mamoru Nishimura, Tomonori Senoh, Takeyuki Ohta, Masako Terao, Noriyuki Shinji, Norio Koide, Takao Tsuji

Abstract

The present study of TbetaRII mRNA expression in PBMC from patients with AIH suggested that the decreased expression of TbetaRII might contribute partially to abnormalities in immune regulation observed in patients with AIH, despite concomitant up-regulation of TGF-beta1 production.