Dynamic Gastric Response to Expansion before and after Vagotomy

Abstract

Jahnberg, T., Martinson, J., Hultén, L. & Fasth, S. Dynamic gastric response to expansion before and after vagotomy. Scand. J. Gastroent. 1975, 10, 593-598.The dynamic gastric pressure response to expansion by direct intragastric air insufflation, 30-50 ml/s, was studied in healthy volunteers, non-operated ulcer disease patients, and in patients operated upon with antrectomy, an-trectomy and vagotomy, or proximal selective vagotomy. Non-operated indi-viduals accepted gastric expansion without considerable increase of pressure. Antrcctomizcd patients showed a higher basal pressure and a moderate in-crease of pressure during expansion. Vagotomized patients, including the ones operated upon with proximal selective vagotomy, demonstrated a marked increase of pressure during expansion. The results indicate that vagal denervation of the corpus-fundus part of the stomach is followed by an impairment of gastric reservoir function.