The Medical Journal of Australia · 1991 · 58 citations · 13 references
MedicineNeurological SurgeryNeurosurgeryAntimicrobial PharmacotherapyMedical MicrobiologySpine SurgeryCentral Nervous System InfectionsSpinal Cord InfectionsSpinal InfectionAcute Spinal InfectionBacterial Spinal InfectionsCausative PathogensEarly DiagnosisEscherichia ColiNeurosurgical DrainageSpinal Cord AbscessSpinal Tuberculosis
OBJECTIVE: To examine the presentation, investigative findings, treatment and outcome in patients with spinal epidural abscess. DESIGN AND SETTING: The study was a retrospective analysis of all patients with this condition presenting to the Neurosurgical Units at the Royal Prince Alfred Hospital and Westmead Hospital, Sydney, during the period September 1984 to September 1987. PATIENTS: There was a total of 21 patients with an age range from 7-87 years (mean 47 years). Eleven cases were acute and ten chronic. The causative organism was Staphylococcus aureus in 15 of the 21 cases, the other organisms involved were Mycobacterium tuberculosis, Escherichia coli, Streptococcus and Pseudomonas aeruginosa. INTERVENTIONS: All patients were treated with a combination of surgery (decompression with or without fusion) and prolonged antibiotic administration. RESULTS: Of the 21 patients 11 had a good to excellent outcome while 10 had a poor outcome. CONCLUSION: The main determinant of outcome was the neurological state at presentation emphasising the importance of early diagnosis and prompt treatment.
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Ann Sullivan Baker, Robert G. Ojemann, Morton N. Swartz et al. · New England Journal of Medicine · 1975 · 790 citations
Nontuberculous Spinal Epidural Infections
A. Price Heusner · New England Journal of Medicine · 1948 · 432 citations
Infectious agents in spinal epidural abscesses
David Kaufman, Jerry G. Kaplan, Nathan Litman · Neurology · 1980 · 222 citations